Biography of Mukhin Nikolai

Father-Mukhin Alexei Alexandrovich-Mother-Dankova Evgenia Vladimirovna-wife-Mukhina Elena Andreevna G. For almost 45 years, N. Mukhina has been associated with the I. Sechenov Moscow Medical Academy, which he finished in the year and where he returned to graduate school at the department of therapy and profiled lobe, after working as a doctor of the polar stations of the Franza-IoSiph- The Department of Therapy and Professor has passed all the subsequent labor activity of Nikolai Alekseevich: first, as an assistant, then an assistant professor, professor and from a year to the present - head of the department and director of the clinic of nephrology, internal and professional diseases E.

Mukhin as a doctor, scientist, and a scientist, and in close cooperation with an outstanding clinician modern academician E. Tareev, who led the department and managed to create an atmosphere of creativity, the cult of science and culture, constant self -improvement in the team. Raised on the principles of the school of E. Tareev - persistent study of etiology, attention to casuistry, a systematic approach to the assessment of diseases, a thorough clinical analysis, taking into account the latest scientific data, Nikolai Alekseevich became a consistent successor of these traditions, these principles were further developed in the works of his students.

One of the main areas of scientific activity of N. Mukhin is the study of the problem of nephrology. The candidate and doctoral dissertations are devoted to the amyloidosis of the kidneys. On a large clinical material, changes are noted in the structure of secondary amyloidosis with an increase in the role of rheumatoid arthritis and tumors in its development, the real frequency of kidney damage with primary and hereditary amyloidosis was first determined, a detailed clinical characteristic of the stages of amyloid nephropathy is given, reflecting the natural evolution of the disease.

For the development of the problem of amyloidosis, N. Mukhin, together with E. Tareev, V. Serov, O. In Russian nephrology, Nikolai Alekseevich persistently introduces the etiological principle of studying the mechanisms of nephritis progression, as well as the study of non -immune mechanisms for the development of the disease, which formed the basis of N. developed by N. mukhroprotective strategy.

Under his leadership, a number of works were performed to identify the role of non -infectious factors of progression, in particular alcohol, disorders of uric acid, environmental lead, cadmium, and drug analgesics. These studies, in essence, formed the basis of a population and preventive direction in the country in nephrology with the creation of population research programs and the development of prevention measures.

An important in practical terms is the concept of a hyperuricemic variant of latent nephritis first put forward by N. Mukhin with a group of employees with the release of its early uricose -cosuric stage, the establishment of risk factors, prevention measures and etiological treatment of this type of jade. The original and priority approaches in nephrology include the use of the method of treatment with glucocorticoids of the method of determining the genetically determined sensitivity to them of cell receptors.

For achievements in the study of the problem of glomerulonephritis N., the problems of pulmonology are also interested in the problems of the wide profile of Nikolai Alekseevich. He and his employees have been done a lot to understand the essence of interstitial lung diseases - idiopathic fibrosing alveolitis and sarcoidosis. In the clinic under the leadership of N.

Mukhina is actively studied by the problems of hepatology: the etiological role of hepatitis viruses in the development of all stages of liver damage, the spectrum of systemic extrahepatic manifestations of chronic viral hepatitis, the possibilities of antiviral therapy, rare forms are Wilson-Konovalov’s disease, primary sclerosing cholangitis, biliary lesions of the liver. The E.

Tareeva clinic has become one of the leading institutions in the study of various systemic vasculitis, including ANCA-Associated, and in general, the problems of diffuse diseases of the connective tissue. The author and co -author near scientific articles in domestic and foreign magazines. Mukhin often makes reports at the congresses of therapists of the country, international and national congresses.

The breadth of the problems being studied, the multidisciplinary composition of patients makes the clinic headed by N. Mukhin, one of the leading medical and scientific and pedagogical institutions, the basis for the training of students of the Moscow Medical Academy named after I. Sechenov, the faculty of fundamental medicine of the Moscow State University named after MSU named after Lomonosov, postgraduate preparation of clinical residency and internships, nephrologists, improving doctors from many regions of the country.

Nikolai Alekseevich possessed an excellent pedagogical gift - his lectures for students and doctors were distinguished by academism, novelty and accessibility of presentation. During scientific counseling and under the leadership of N. Mukhin, 8 doctoral and 48 candidate dissertations were performed.In the year he was elected a corresponding member, and in the year-an academician of the Russian Academy of Medical Sciences.

He was awarded the Order of Honor, medals, other insignia.